Thursday, August 31, 2023

Specifications: 12-Months Fixed Term – Contract
Salary: £42,000 per annum  
Location: UK – Remote/Flexible
Closing date: 13 Sep 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into five directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

Reporting to the Senior Managing Editor and working with members of the Editorial Production and Methods Directorate, the role holder will need to have good awareness of Cochrane guidance for different types of standard and complex systematic reviews (intervention, qualitative, diagnostic test accuracy, prognosis, rapid and overview), plan how they will need to be handled in their team, and work to ensure that deadlines are met. The role holder will also be required to ensure that pilots aimed at innovating the editorial process can be supported as needed.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here.
• The deadline to receive your application is 13th Sep, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Thursday, August 31, 2023 Category: Jobs

社会心理措施介入可以减少疗养院居民的抗精神病药物治疗吗？ 关键信息 我们不确定针对疗养院居民进行社会心理措施介入是否能有效减少其抗精神病药物使用。该研究使用了多种方法并显示不一致的结果，但似乎很难将结果推广到不同的健康、社会照护体系。没有证据显示社会心理措施介入会导致危害事件，如：意外跌倒或病人入院等。 为什么疗养院居民要服用抗精神病药物？ 许多疗养院居民患有失智症，在患病过程中的某些时候会出现情绪或行为问题，特别在疾病后期更为常见。对于居民本身和他们的照顾者来说，症状可能是严重和痛苦的，包括焦虑、不安和徘徊、幻觉（看到或听到不真实存在的东西）以及对他人的攻击行为。护理人员面临居民的挑战性行为，并分析这些行为的原因、前因或后果。 通常使用抗精神病药物来控制这些症状和行为。这些药物主要用于治疗与精神病相关的疾病（导致人们对事物的感知或解释与其他人不同的心理健康问题），但也用于治疗具有与精神病类似症状的其他疾病，例如失智症。这些药物并不一定有效果，对于失智症病人甚至可能有危害。因此，指引建议只有在非药物策略不起作用时才应使用它们。 我们想了解什么？ 由于抗精神病药物对失智症益处有限且存有潜在危害，因此我们对于降低疗养院使用抗精神病药物的方法感兴趣。这些方法可能包括组织因素、员工教育训练或其他介入措施。我们对于照护组织、提供方式与推广替代性非药物策略等社会心理介入措施感兴趣。介入预措施...

对于需要透析的肾衰竭疲劳病人进行介入措施是否有效？ 研究问题 疲劳是一种常见且令人虚弱的症状，可能会限制透析患者的生活参与度。造成他们的生活质量降低，并与心血管疾病、死亡和抑郁有关。一些潜在的介入措施曾被拿来做影响评价，包括药物或非药物治疗，如运动、饮食、按摩、芳香疗法、穴位按摩。 我们做了什么？ 我们对接受血液透析或腹膜透析的成人及儿童，评价药物或非药物介入措施对控制疲劳是否有效。我们评价所有可取得的临床研究，对结果进行总结。并使用GRADE系统，以判定疲劳介入措施相关证据的质量。 我们发现了什么？ 我们纳入研究共94项，包含随机受试者8191名。这些病人接受药物、非药物、标准护理或安慰剂。介入方式是随机分配的。通常是数月的短期研究。但都不包括儿童。与安慰剂或标准护理相比，运动、芳香疗法、按摩和穴位按摩可以改善疲劳。药物或其他非药物介入方式对透析患者的影响尚不确定。 研究结论 与安慰剂或标准护理相比，运动、芳香疗法、按摩和穴位按摩可以改善疲劳。与安慰剂、标准护理或其他治疗方法相比，药物或非药物介入是否对透析患者的疲劳有影响仍不确定。 如果您发现此证据有帮助，请考虑向 Cochrane 捐款。我们是一家慈善机构，提供可获取的证据来帮助人们做出健康和护理决定。捐赠 作者结论:  与安慰剂、标准治疗或不干预相比，运动、芳香疗法、按摩和穴位按摩可以改善疲劳。药物和其他非药物干...

不同的皮质类固醇透过静脉注射对于预防早产儿支气管肺发育不全有何益处和风险？ 关键信息 ‧ 在本次文献回顾中，我们使用了网络meta分析（network meta-analysis, NMA），这是一种相对较新的工具，可以对所有相关治疗方式进行比较，包括在先前的临床试验中尚未被相互比较的方式。 ‧ NMA能够在现有数据中添加一些信息，最重要的是它能比较不同皮质类固醇剂量对于预防早产儿支气管肺发育不全（bronchopulmonary dysplasia, BPD）的效果。 ‧ 由于尚未出现足以引导决策的长期有害证据，因此给予皮质类固醇的最佳方法仍属未知。 什么是BPD？ 早产儿可能会出现肺损伤，称为支气管肺发育不全，这可能会产生严重且持续性的有害影响。 如何预防支气管发育不全？ 称为皮质类固醇的消炎药物可以通过其抗发炎特性来减少BPD的产生，但它们也有其自身的潜在风险。能够平衡这些益处和风险的最佳皮质类固醇治疗计划尚属未知，其变因包括使用哪种类型的皮质类固醇（选择地塞米松或氢化可的松）、皮质类固醇的剂量以及开始治疗的年龄。 我们想探讨什么？ 在该综述中，我们想要比较对早产儿施以系统性的不同皮质类固醇治疗方案（包括皮质类固醇的类型、剂量和治疗时间点）所产生的益处和风险。这些治疗方案主要是经由静脉注射给予的。 我们做了什么？ 我们纳入了一些试验，这些试验评价了皮质类固醇治疗引发早产儿B...

When it comes to starting a family, timing is everything

A new Cochrane review of methods to increase chances of successful conception suggests that timed intercourse using urine ovulation tests probably improves live birth and pregnancy rates in women under 40 who had been trying to conceive for less than 12 months, compared to intercourse without ovulation prediction.

The Cochrane review, conducted jointly with researchers from University of Oxford, the Royal Berkshire Hospital in Reading, and the Princess Anne Hospital in Southampton, included seven randomised controlled trials involving 2,464 women or couples who had been trying to conceive.

Each month there is a narrow window for successful conception due to the limited lifespan of the sperm and egg, which begins from around five days before ovulation (egg release) and lasts until several hours afterwards.

The period of a woman’s cycle can be identified by different methods, including urine ovulation tests (dipstick devices that can detect changes in hormones released into the urine, signifying when ovulation will occur), fertility awareness-based methods (FABM) (including calendar tracking, monitoring changes in cervix fluid and body temperature) or identifying when the egg is released on ultrasound. This review aimed to assess the benefits and risks of timed intercourse on pregnancy, live birth, negative effects and quality of life in couples trying to conceive.

The study found that timing intercourse around the fertile period using a urine ovulation test increased the chances of pregnancy and live birth to between 20% to 28%, compared to 18% without using urine ovulation tests. This was specifically in women under 40 trying to conceive for under 12 months.

Tatjana Gibbons, a DPhil researcher at Oxford’s Nuffield Department of Women's & Reproductive Health and lead author on the study, said: ‘‘Many couples find it difficult to achieve a pregnancy, which can lead to concerns about their fertility.'

The finding that a simple and easily available urine test can increase a couple’s chance of successful conception is quite exciting because it can empower couples with more control over their fertility journey and could potentially reduce the need for infertility investigations and treatments."

 

Professor Christian M Becker of Nuffield Department of Women's & Reproductive Health said: "The high threshold of evidence required in a Cochrane review makes even this moderate quality evidence for the effectiveness of urine ovulation tests quite impressive, as well as surprising considering how long they have been available for."

However, the researchers cautioned that because many of the studies were funded by the manufacturers of the urine ovulation test, the results should be interpreted with caution.

They also found that there was insufficient evidence to conclude the effect of the other methods in the study, including timed intercourse on clinical pregnancy (ultrasound-confirmed pregnancy), the use of FABM in timed intercourse compared to intercourse without ovulation prediction.

• Read the plain language and full review on the Cochrane Library 

Gibbons T, Reavey J, Georgiou EX, Becker CM. Timed intercourse for couples trying to conceive. Cochrane Database of Systematic Reviews 2023, Issue 9. Art. No.: CD011345. DOI: 10.1002/14651858.CD011345.pub3. 

Friday, September 15, 2023

Wednesday, August 30, 2023

Wednesday, August 30, 2023

The Cochrane Early Career Professionals group aims to provide its members opportunities to enhance their knowledge, skills, and expertise by providing a platform for international networking with early career professionals or other members in the Cochrane community. They aim to focus on the development of leadership skills for the early career members of the Cochrane community and encourage the active involvement of the Early Career Professionals in shaping the mission and vision of the Cochrane community.

The team of Cochrane Early Career Professionals will be chatting with senior researchers and members of Cochrane on a podcast called 'Conversations with Cochrane'. Through the podcast episodes, you can learn about citizen science, issues around open-access, elements of review production, methods used in evidence synthesis, and how to get involved in Cochrane. 

"At Cochrane, nurturing aspiring minds and supporting professionals embarking on their career journey is part of the work we do. Our commitment is evident through initiatives like the Cochrane US Mentorship,  Cochrane International Mobility,  the student pathway to Cochrane Membership, and the Cochrane Early Career Professionals Network.

The podcast from the Early Career Professionals network is a great addition and we're looking forward to all the insight conversations to come - and that everyone can be a part of that!" 

- Rachel Klabunde, Interim Head of Membership, Learning and Support 

 

"We are really excited to introduce Cochrane ECP’s first podcast 'Conversations with Cochrane'! There are many ways in which early career professionals can get involved in Cochrane and develop leadership skills to support a scientific research career – follow our podcast and stay tuned for news and exciting opportunities!"

- Dr Elpida Vounzoulaki, Podcast Host and Chair of the Cochrane ECP group

'Conversations with Cochrane' is available in your favourite podcast app and on Spotify, Apple Podcasts, and Amazon Music. 

Below is a listing of current episodes. 

An introduction to the Conversations with Cochrane podcast from current and future leadership of the Cochrane Early Career Professionals Network by Drs. Elpida Vounzoulaki, Santiago Castiello, and Neal Christopher. Listen as we introduce the aims and scope of this series. 

• Spotify
• Apple Podcasts
• Amazon Music

Monday, August 28, 2023

Cochrane, a global independent network of researchers, professionals, patients, carers, and health enthusiasts is celebrating our 30th anniversary in 2023.

In 1987, the year before Archie Cochrane died, he referred to a systematic review of randomized controlled trials of care during pregnancy and childbirth as "a real milestone in the history of randomized trials and in the evaluation of care", and suggested that other specialties should copy the methods used. His encouragement, and the endorsement of his views by others, led to the opening of the first Cochrane Centre in Oxford, UK in 1992 and the founding of The Cochrane Collaboration in 1993.

Cochrane has released a new video to celebrate our 30 year anniversary, featuring interviews with key collaborators past and present.

At the #CochraneLondon Colloquium, Karla Soares-Weiser and Jimmy Volmink engaged in a thought-provoking discussion with Iain Chalmers, Muir Gray,  Jini Hetherington, and others. They explored the origins and inspirations behind the founding of Cochrane. View the PDF Slides.

We have also curated a collection of Cochrane Reviews that exemplify the enduring mission and innovative approaches taken by our organization. This Special Collection underscores the future of Cochrane, built upon its rich history of methodological diversity and unwavering dedication to meeting user needs.

• Visit the Cochrane Library Special Collection 
• Learn more about Cochrane's history 
• Purchase limited edition Cochrane 30th Anniversary items

Monday, October 2, 2023

Friday, August 25, 2023

Friday, August 25, 2023

激素疗法能否改善绝经期或绝经后女性的性功能？ 关键信息 • 与安慰剂相比，单独使用雌激素（与女性性和生殖发育相关的激素）可能会提高性功能评分。 • 与安慰剂或未治疗相比，我们不确定雌激素加孕激素（另一种女性激素）、合成类固醇（如tibolone）、选择性雌激素受体调节剂（SERMs）（能影响雌激素作用）或SERMs联合雌激素对性功能的影响。 • 研究结果差异可能是由于激素治疗类型、剂量以及用于评估的问卷不同所造成的。 什么是更年期及其对女性的影响？ 更年期是女性月经停止的时候，通常在45至55岁左右。在更年期，卵巢逐渐停止产生雌激素，即调节月经的激素。雌激素的减少可以在月经停止前（围绝经期）、更年期和更年期后（绝经后）引起不良症状。症状包括情绪变化、潮热及盗汗。性交疼痛、对性生活缺乏兴趣以及性唤醒或性高潮障碍等性生活相关主诉在绝经后很常见，可能会影响女性的自尊、自信和性健康。 什么是激素疗法，它如何帮助女性的性功能？ 激素疗法由一种激素或多种激素联合组成，有助于减缓更年期症状。可经由皮肤贴片、喷雾剂或凝胶、片剂或植入物的形式给药，用于治疗各种围绝经期和绝经后症状。激素疗法可以通过增加阴道组织的润滑、血液循环及感觉来改善影响性功能的症状，如干涩、瘙痒及性交疼痛。 我们想知道什么？ 我们想了解激素疗法是否能改善女性的性功能，以及更年期不同阶段的效果是否不同。同时也想了解哪种类型的激素...

Specifications: Permanent – Full Time
Salary:  £27,070 per Annum  
Location: (Remote – Flexible) Candidates anywhere from the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: EPM
Closing date: 06 September 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

To provide an efficient and responsive administrative, organisational, and logistical service to the Editor in Chief (EiC) and the leadership team of the Evidence Production & Methods Directorate (EPM). Support operational activities of the directorate, including management of the Editorial Board.
       
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everyting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 6th Sep, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Wednesday, August 23, 2023 Category: Jobs

Tuesday, August 22, 2023

心理健康急救：改善心理健康和福祉的工具 本系统综述为何重要？ 心理健康急救的定义是“向正在出现心理健康问题、心理健康问题恶化或处于心理健康危机中的人提供帮助”，急救工作一直持续到获得适当的专业帮助或危机解除为止。 心理健康急救（Mental Health First Aid，MHFA）是一项培训计划，旨在向公众教授心理健康急救策略。MHFA培训在级联模型中运作；通过经认证的讲师提供培训，使学员掌握心理健康急救技能。接受培训后，学员可以在其工作场所、组织或社区内为人们提供心理健康急救服务。MHFA培训旨在提高人们对心理健康问题的认识，从而减少人们对这些问题的偏见。学员会学习如何为受助者提供即时帮助，以及如何引导他们寻求服务。 哪些人会对本系统综述感兴趣？ 考虑参加MHFA培训的人 员工和雇主 政策决策者 本系统综述要回答什么问题？ 心理急救（MHFA）培训对心理健康和福祉、心理健康服务的使用情况以及对社区中接受MHFA培训的个人的不良影响有什么影响？ 本系统综述纳入了哪些研究？ 我们检索了截至2023年6月发表的研究MHFA培训的随机对照临床试验（将人们随机分为两个或多个治疗组的临床研究）。 我们纳入了21项研究，涉及22604名受试者。 本系统综述的证据可以告诉我们什么？ 主要关注的结局是在6个月至1年的时间点上，研究MHFA培训对个人心理健康和福祉的影响。我们纳入了三项比较：接...

Monday, August 21, 2023

Cochrane appoints new Governing Board interim Chair, Jordi Pardo Pardo and says farewell to two outgoing Trustees, Catherine Marshall and Tracey Howe

Cochrane is an international non-profit network, which sets the gold standard for synthesizing health research findings  to facilitate evidence-based health care.  Cochrane Reviews, found in the Cochrane Library, are up-to-date, follow a rigorous scientific methodology, and are free from commercial conflicts of interest. Health professionals, patients, and policy makers trust Cochrane Reviews for their healthcare decision-making. Cochrane works with researchers, health professionals, patients, policy makers, and media representatives from around the world to make Cochrane Reviews relevant and usable.

Cochrane's Governing Board is responsible for setting Cochrane's strategic direction and overseeing the work of the Chief Executive Officer, Editor in Chief, and Central Executive Team.

Cochrane’s Governing Board has appointed Jordi Pardo Pardo as new interim Chair. He will be taking over from Catherine Marshall and Tracey Howe who have been serving as Co-Chairs of the Board. Catherine's maximum four-year term will conclude in September 2023, and Tracey, whose term was set to end September 2024, has decided to step down this September due to personal circumstances.

Jordi Pardo Pardo, a longstanding member of the Board, former Managing Editor of Cochrane Musculoskeletal and current senior advisor with the Health Equity Thematic Network, will be taking over as interim Chair, effective from 5th September 2023. His appointment was made by the Governing Board during their May meeting. Jordi will serve in this role for a period of up to one year while a permanent Chair is recruited. The Governance and Nomination Committee will oversee the recruitment process and make a recommendation to the Board of Trustees.

Jordi’s tenure with Cochrane dates back to 1997 when he joined the Iberoamerican Cochrane Centre and contributed to the expansion of the Iberoamerican network. He has been part of the Lung Cancer group, the Equity Methods Group, Cochrane Canada and Cochrane Musculoskeletal, before joining the newly created Equity Thematic Network.

"I'm humbled by the opportunity to expand on the work that Tracey and Catherine have led to transform our organization. As we navigate into a new structure, I’m excited to explore the opportunities that a move to open access could bring to Cochrane and the world. I’m looking forward to working with our talented community to grow our reach and impact.”

- Jordi Pardo Pardo

Catherine Spencer, Cochrane CEO, extended a warm welcome to Jordi as interim Chair observing: “Jordi Pardo Pardo has an excellent understanding of both the workings of the Governing Board and the purpose of Cochrane. His appointment is welcomed by the Central Executive Team to ensure continuity as Catherine Marshall and Tracey Howe’s time comes to a close.”

She further expressed sincere gratitude to Catherine and Tracey for their unwavering dedication, leadership and invaluable contributions to Cochrane while wishing them all the best in their future endeavours.

• Learn more about Cochrane's governance and management

Tuesday, August 22, 2023

Specifications: Permanent – Full Time
Salary:  £60,000 per Annum (1.0 FTE)
Location: Remote – UK Based
Closing date: 04 September 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Head of Editorial Policy and Research Integrity is responsible for Cochrane’s editorial policies and research integrity and methods standards. They will ensure Cochrane’s review production processes and systems support efficient and trusted review production, with a focus on improving author experience. This role involves editorial and operational leadership, working closely with colleagues across the Evidence Production & Methods and Publishing and Technology directorates to ensure Cochrane’s product development aligns with its strategic priorities.   

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive on boarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 04th Sep, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, August 21, 2023 Category: Jobs

Monday, August 21, 2023