Specifications: Permanent – Full Time Role
Salary:  £60,000 per Annum  
Location: (Remote – Flexible) Candidates anywhere from the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: DEV
Closing date: 25 June 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

To lead the Membership, Learning & Support department in providing strategically-focussed services, providing intelligent pathways for people to get involved through membership, communicating and engaging with them in innovative ways to strengthen and develop their relationship with Cochrane, shaping and offering high quality learning experiences, and supporting people with their enquiries.   

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here 
• The deadline to receive your application is 25 June 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, June 5, 2023 Category: Jobs

Specifications: Permanent – Part Time (2 days a Week)
Salary:  £40,000 per annum  (pro rata)
Location: Remote – Flexible
Directorate: DEV
Closing date: 21 June 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

As a new role within the Communications team, the Creative Content Producer will work with colleagues across the organisation to bring our work to life and ensure our branding and visual identity are applied consistently. We’re looking for a self-starter who will be able to take ideas from concept through to final design, working flexibly with colleagues across the organisation.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

Cochrane has offices with payroll in the UK, Germany and Denmark. Candidates from other countries are employed on consultancy contracts. If you would like more details on how this works, please contact hrenquiries@cochrane.org

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 21 June 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, June 5, 2023 Category: Jobs

在骨盆、髋部或长骨创伤手术中，旨在减少手术期间失血的药物是否有效？它们是否会造成不良影响？ 关键信息 • 我们还不知道在骨盆、髋部或长骨（大腿骨）创伤手术期间减少出血和输血的最佳药物。 • 一些研究仍在进行中；当他们完成后，我们希望能够得出更好的结论。 研究背景 骨盆、髋部和长骨骨折可能导致大量出血，如果需要手术修复骨折，还会导致进一步失血。长骨是具有轴和两端且长度大于宽度的骨头。这包括大腿骨、小腿骨、手臂和锁骨。骨折和随后的手术会带来输血和贫血的风险。贫血是指红细胞数量或其中的血红蛋白浓度低于正常水平。血红蛋白将氧气输送到全身——血红蛋白水平低会导致疲劳、虚弱、头晕和呼吸短促等症状。 为什么在血管手术期间减少输血很重要？ 如果患者在此类手术期间或之后大量出血，他们可能需要输血来补充失去的血液。如果可能的话，最好避免接受输血，因为输血会造成伤害。当卫生服务机构血液供应有限时，这一点尤为重要。药物可以减少输血需求及其相关并发症，改善患者预后，并降低医疗成本。此类药物的例子是氨甲环酸和重组因子VIIa。然而，它们可能会引起不良影响，例如血栓。 我们想知道什么？ 我们想要发现在成人骨盆、髋部或长骨骨折的手术中，是否有药物可以帮助减少失血。我们还想找出哪种有效的药物最有效。减少失血可以降低贫血和需要输血的风险。它还可以降低因先前出血而需要再次手术止血或清除大量血液（血肿）的风险。 我们做...

哪种吸入药物组合治疗慢性阻塞性肺病（chronic obstructive pulmonary disease, COPD）是安全有效的？ 关键信息 •与LABA加吸入皮质类固醇（LABA+ICS）相比，使用含有长效毒蕈碱拮抗剂加长效β受体激动剂（LAMA+LABA）的吸入剂治疗慢性阻塞性肺疾病（chronic obstructive pulmonary disease, COPD）可能会改善呼吸功能并降低肺炎风险。 • LAMA+LABA和LABA+ICS在減少COPD恶化和改善生活质量方面可能效果相同。 • 服用LAMA+LABA的人其死亡风险略高。 什么是慢性阻塞性肺病？如何治疗？ 慢性阻塞性肺病（chronic obstructive pulmonary disease, COPD）是一种长期肺部疾病，其特征是咳嗽、咳痰（来自肺部的液体，即痰）和呼吸困难。 慢性阻塞性肺病可以使用“支气管扩张剂”药物进行治疗，这种药物可以通过放松肺部肌肉和扩宽气道来使呼吸变得更容易。支气管扩张药的两种主要类型是长效毒蕈碱拮抗剂（long-acting muscarinic antagonists，LAMA）和长效β受体激动剂（long-acting beta-agonists，LABA）。现在，医疗保健指南建议患有稳定、高风险COPD的患者使用含有LAMA+LABA组合药物或LABA+吸入...

用于治疗儿童和青少年性虐待后果的心理干预效果如何 关键信息 • 许多心理疗法被用来帮助儿童和青少年克服性虐待的后果。 • 很大程度上不确定的证据表明，在帮助儿童和青少年从性虐待中恢复过来方面，任何特定的干预措施都优于常规管理。 • 我们需要对干预措施进行更多更好的研究，以确定在解决性虐待的各种后果方面，一种干预措施是否优于另一种干预措施。 我们所说的心理干预是什么？ 心理干预是那些试图给人们带来改变的干预。它们通常被称为“谈话疗法”，但它们也纳入治疗师和患者之间基于活动（例如游戏或艺术）进行交流的疗法。 有一系列心理干预措施可用于帮助遭受性虐待的儿童和青少年克服因虐待而可能出现的各种困难；例如，创伤后应激障碍（post-traumatic stress disorder, PTSD）、焦虑、抑郁和一系列行为问题。 为什么这对遭受过性虐待的儿童和青少年很重要？ 以前的系统评价表明，心理疗法可以改善儿童的结局，但我们不知道某些疗法是否比其他疗法更有效。 我们预期发现什么？ 我们想找出哪些干预措施最适合治疗性虐待后可能出现的一系列问题。我们想知道我们是否可以按照它们的效果对它们进行排名。例如，我们想找出哪种干预最能帮助患有PTSD的儿童或抑郁的儿童。哪个第二好？等等。 我们做了什么？ 我们检索了检验一系列心理疗法有效性的研究，包括认知行为疗法（cognitive-behavioural...

Specifications: Permanent (3 days a week)
Salary:  £36,952 per annum  (pro rata)
Location: Remote – Flexible
Directorate: Development  
Closing date: 18 June 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

Cochrane is looking for a part time (three days a week) Communications Officer to write engaging copy for a range of audiences. This is an exciting opportunity to work with one of the world’s most trusted sources of health and care evidence. You would be helping to share important high-quality evidence with a wide range of people, empowering them to make better health and care decisions.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

Cochrane has offices with payroll in the UK, Germany and Denmark. Candidates from other countries are employed on consultancy contracts.

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 18th June, 2023
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Thursday, June 1, 2023 Category: Jobs

益生元预防早产儿坏死性小肠结肠炎 系统综述问题 益生元是否能有效预防极早产儿或极低出生体重儿发生坏死性小肠结肠炎？ 研究背景 极早产（早产超过8周）和极低出生体重（小于1.5公斤）的婴儿有罹患坏死性小肠结肠炎的风险，这种严重的情况会使婴儿的肠道内壁发炎和坏死，并可能与死亡、严重感染、长期失能与发育问题有关。帮助预防坏死性小肠结肠炎的一种方法可能是在奶中添加益生元（不易消化的糖链，以支持健康“益生菌”的肠道定植）。 我们做了什么？ 我们检索了研究益生元对极早产儿或极低出生体重儿罹患坏死性小肠结肠炎风险影响的试验。我们比较和总结了这些试验的结果，并根据研究方法与规模等因素，来评估了证据的可信度。 我们发现了什么？ 我们发现7项试验，共涉及705名婴儿受试者。试验大多规模较小，而且大多数都存在设计缺陷，可能会使结果产生偏差。 主要研究结果 综合分析表明，给予极早产儿或极低出生体重儿益生元，可能对坏死性小肠结肠炎、死亡或严重感染的风险几乎没有影响，但我们对此证据缺乏可信度。一项试验评估了对失能或发育结果的影响，但我们对此证据缺乏可信度。 证据的局限性是什么？ 因为担心纳入试验中所使用的方法，可能对于益生元的好处有了夸大结果的偏差，且一些效果估计不精确，我们对坏死性小肠结肠炎、死亡和严重感染影响的证据几乎没有可信度（对失能或发育结局的影响也几乎没有可信度）。 证据的时效性如何？ 此证据更新...

Wednesday, May 31, 2023

Title: Editorial Policy Lead
Specifications: Fixed term contract (six months with potential to extend to 12 months)
Salary:  £ 52, 000 per Annum
Location: Ideally based in the UK, Germany or Denmark. Candidates from the rest of the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: Evidence Production and Methods
Closing date: June 18, 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high-quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Editorial Policy Lead will lead the development and implementation of editorial policies and related procedures for the Cochrane Database of Systematic Reviews and associated products. They will work closely with the Methods Support and Review Development team and Central Editorial Service to ensure that all content published on the Cochrane Library meets high standards of quality, accuracy, and transparency. Overall, this role will contribute to streamlining editorial policy procedures with a focus on author experience, to support Cochrane’s efficiency and sustainability as an organisation.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

• An opportunity to truly impact health globally
• A flexible work environment
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply"

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 18h June, 2023
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
•       Read our Recruitment Privacy Statement

 

Monday, May 29, 2023

Title: Legal Counsel
Specifications: Permanent Role (open to part-time minimum 4 days per week)
Salary: £55,256K per annum
Location: UK Remote (office in London is available if candidate wants to use it sometimes)
Directorate: Finance & Corporate Services
Closing date: 20 June 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high-quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production & Methods, Publishing & Technology, Development, and Finance & Corporate Services[CE1] .

The Legal Counsel will be required to provide legal advice across the organisation, to enable Cochrane to manage risk and meet its legal and regulatory obligations. The successful candidate will be a qualified solicitor with excellent communication skills, who can provide clear and pragmatic advice and manage their workload effectively whilst maintaining attention to detail.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

• An opportunity to truly impact health globally
•  A flexible work environment
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply:

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 20 June 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Thursday, May 25, 2023 Category: Jobs

Early bird registration has been extended for the 2023 Cochrane Colloquium. Register by Wednesday 7 June 2023 to get the reduced early bird rate

You can register for the Cochrane Colloquium, which will take place at the Queen Elizabeth II (QEII) Centre in London from 4th to 6th September 2023, with Satellite events on 3rd September.

The Colloquium is an annual event for everyone with an interest in the use of evidence in healthcare decision making including those engaged in evidence production, co-production, dissemination, implementation, and policy making, as well as those making individual healthcare decisions.

This year’s theme is ‘Forward together for trusted evidence’. It will explore the challenges for the future around the trustworthiness of healthcare data and information whilst also celebrating 30 years of producing trusted evidence. 

You can explore the programme here and the list of plenary speakers here – with more to be added.

Students, healthcare consumers, and people from low-income, lower-middle-income, and upper-middle-income economies (LMIC) are eligible for a reduced rate.

Satellite events:

 On Sunday 3rd September, there are three satellite events taking place at the Colloquium venue that you may also like to register for:

• 2023 Cochrane Methods Symposium
• GRADE-CERQual event
• Putting evidence into practice: an event for students and healthcare professionals

 Find out more about these satellite events, including how to register, here.

Register today:

• Register here
• Registration fees – reduced early bird rate now ends on 07 June 2023
• Registration terms and conditions

Further information:

• Colloquium website 
• #CochraneLondon
• Press contact: Katie Abbotts, Cochrane UK
• Sign up for newsletter updates

Thursday, June 1, 2023

Thursday, May 25, 2023

Thursday, May 25, 2023

Wednesday, May 24, 2023

肥胖和COVID-19不良结局 肥胖对COVID-19的结局有何影响？ 关键信息 • 有足够的证据证明：极度肥胖（BMI>40kg/m 2 ）会增加因COVID-19导致的死亡、机械通气需要、住院和入住ICU的几率。 • 肥胖通常会导致患者需要机械通气。 • BMI越高，患COVID-19导致的重症疾病的几率就越大。 肥胖定义 肥胖被定义为人体不同部位异常或过多的脂肪堆积，并对健康构成威胁。为评估肥胖，可以使用不同的指数，例如体重指数（body mass index, BMI），即一个人的体重（千克）除以身高（米）的平方。世界卫生组织将肥胖分为三类。根据该分类，I级肥胖的BMI范围为30至35kg/m 2 、II级肥胖为35至40kg/m 2 、III级肥胖为40kg/m 2 及以上。 研究预期结果 研究目的是了解肥胖是否对死亡率、机械通气需要、住院治疗、ICU入住、因COVID-19导致的严重疾病或肺炎产生影响。 研究方法 对医学数据库进行了系统检索，筛选2019年12月至2021年4月期间肥胖与死亡率及其他结局之间关联的证据。随后根据证据质量、研究样本和研究质量对纳入研究进行分类和分级。 研究发现 共纳入171项符合条件的研究，其中149项研究（12045976名受试者）为至少一项Meta分析提供定量数据。就结局而言，111项研究报告了死亡率、48项研究报告了机械通气需...

Introducing "Las claves de la evidencia en salud" by Cochrane Iberoamerica—a dynamic Spanish course that delves into evidence-based healthcare, clinical trials, and Cochrane evidence. Designed for healthcare consumers (patients, care givers, family members), policy makers, and the healthcare team, this interactive course offers five modules, each estimated to take 30-40 minutes to complete. Best of all, it's completely free with a Cochrane account (registration for Cochrane account is also free).

The course offers interactive learning with reading materials, videos, quizzes, and other assessments. It follows the personal journey of 'Elena,' a fictional consumer, but participants can explore modules freely. It has been co-produced by healthcare consumers, researchers, and Cochrane specialists. The original English version, "Evidence Essentials", was translated and adapted by the Iberoamerican Cochrane Center.

"We are convinced that this course is a relevant and user-friendly contribution to disseminate to the Spanish-speaking public how we know if a treatment works and what is the process to generate scientific evidence for health care. At the Iberoamerican Cochrane Center we translate all Cochrane systematic reviews into Spanish and this new course in Spanish is an ideal addition to improve the use of all this evidence in health care", says Gerard Urrútia, director of the Iberoamerican Cochrane Center and the Iberoamerican Cochrane Network.

"We'll promote it in Spain and the 18 countries of the Iberoamerican Cochrane Network to enhance understanding of evidence in health," adds Urrútia. "It targets healthcare users and professionals, complementing other resources we provide."



"We are going to disseminate this course in Spain and in the other 18 countries that are part of the Iberoamerican Cochrane Network as a first gateway to learning the key elements of evidence in health," adds Urrútia. "Our target audience is not only health care users, but also all those who are not familiar with systematic reviews and need to make healthcare decisions, including healthcare professionals. These modules will also support the numerous resources and dissemination activities that we produce for the Spanish-speaking public, such as Nutrimedia or Cochrane responde."

Check out this free online resource in Spanish or the other three languages today! 

• Evidence Essentials
• Las claves de la evidencia en salud
• Evidenz verstehen - ein Onlinekurs von Cochrane
• Основы Доказательств Кокрейн

Tuesday, May 23, 2023

Monday, May 22, 2023

It is with great sadness that we mark the passing of Hyeong Sik Ahn, Director of Cochrane Korea, Professor at the Department of Preventive Medicine, and former Dean of the Graduate School of Public Health at Korea University.

Professor Ahn's enduring relationship with Cochrane, spanning over twenty years, began when he attended his first Cochrane Colloquium in 2002. This initial gathering in Norway fueled his determination to introduce Cochrane principles in Korea. In 2007, Professor Ahn led the establishment of the Korean Branch of the Australasian Cochrane Center. Two years later, Cochrane Korea was officially inaugurated at Korea University as a geographical group of Cochrane.

Beyond his Cochrane-related activities, Professor Ahn organized the 8th Guidelines International Network Conference in the summer of 2011, themed "Linking Evidence, Policy, and Practice," marking the first time the conference was held in Asia. In 2014, he authored an influential article published in the New England Journal of Medicine titled "Korea's Thyroid Cancer 'Epidemic' – Screening and Overdiagnosis." This article highlighted Professor Ahn's determination to address overdiagnosis, particularly within the Korean healthcare system.

One of the highlights of Professor Ahn's academic career was hosting the 24th Cochrane Colloquium in the fall of 2016 in Seoul, where colleagues and researchers from around the world gathered for a successful conference that the Cochrane Korea team fondly remembers. In 2015, he spearheaded the implementation of the Choosing Wisely Korea campaign, aimed at reducing unnecessary medical tests and treatments in the country. By 2022, the campaign had gained endorsement from twenty-seven Korean medical societies.

"Professor Ahn played a pivotal role in establishing Evidence-Based Medicine in Korea," says Catherine Spencer, CEO of Cochrane. "To the fortunate students and colleagues who knew him, his passing represents an immeasurable loss. He will be deeply missed."

Professor Hyun Jung Kim, who served as co-director alongside Professor Ahn, will now assume the role of Director of Cochrane Korea, carrying forward Professor Ahn's inspiring legacy.

• Visit the Cochrane Korea website

 

 

 

Friday, May 19, 2023

Cochrane, a global independent network of researchers, professionals, patients, carers, and health enthusiasts, proudly announces the publication of its latest Special Collection titled "Cochrane at 30: what our 30th year can tell us about the future." 

In an era where access to health evidence has expanded, the risk of misinterpreting complex content has grown, while the likelihood of individuals obtaining a comprehensive and balanced understanding has diminished. Cochrane's role in providing accessible, credible information to support informed decision-making has never been more critical in improving global health.

At the heart of Cochrane's mission is the collaborative production of trustworthy health information devoid of commercial sponsorship and conflicts of interest. This commitment enables the generation of authoritative and reliable evidence, unconstrained by commercial and financial interests. Cochrane's systematic reviews, which gather and analyze the best available evidence, are recognized globally as the gold standard for reliable and high-quality information.

The need for Cochrane's work is even greater than it was when we started in 1993. In an era where access to health evidence has expanded, the risk of misinterpreting complex content has grown, while the likelihood of individuals obtaining a comprehensive and balanced understanding has diminished. Cochrane's role in providing accessible, credible information to support informed decision-making has never been more critical in improving global health.

To commemorate Cochrane's 30th anniversary, we have curated a collection of Cochrane Reviews that exemplify the enduring mission and innovative approaches taken by our organization. This special collection underscores the future of Cochrane, built upon its rich history of methodological diversity and unwavering dedication to meeting user needs.

• View the Cochrane Library Special Collection

 

 

Friday, May 19, 2023

成人肝移植后的运动干预 研究背景 接受肝移植后，身体活动水平会下降。对于通过运动干预来预防心肺疾病、高血压、2型糖尿病、痴呆、非酒精性脂肪肝病（由于肝脏脂肪积累引起的疾病）、癌症或其他可能迅速发展的威胁生命的疾病，其益处和伤害尚未得到充分研究。 研究目的 我们想要确定成人肝移植后运动的益处和伤害。 研究方法 我们在医学数据库中检索了在肝移植患者中进行的、设计良好的临床试验，比较了任何类型的运动与不运动、安慰剂干预或其他类型的运动的情况。 研究结果 我们纳入了三项随机临床试验，包含241名受试者，其中199名受试者完成试验。随机试验是一种将受试者随机（仅由偶然机会决定）分配到试验组或对照组的研究方法。这些试验在美国、西班牙和土耳其进行在不同试验中，运动持续时间分別为 2 个月、6 个月和 10 个月。所有研究都比较了运动干预与常规照护。所有试验均包括接受肝移植的成年人。这三个试验评估了不同运动干预（有氧运动，抗阻运动或两者兼有），以及不同类型的监督和形式（如有无监督，个体或团体运动）。有氧运动指的是一种重复、有结构的身体活动类型，需要人体的新陈代谢系统利用氧气产生能量。有氧运动是一种持续的运动，可以增加血液流向肌肉，加强心血管系统和肺功能。抗阻训练（力量训练）是一种通过对抗外部阻力来锻炼肌肉或肌肉群的形式，其目的是改善肌肉的健康程度。抗阻训练包括诸多形式，例如使用自由重量、健身器械...