计划在医院分娩与计划在家分娩 问题是什么？ 大多数健康女性的怀孕都是正常的，并且大多数分娩都可以在没有不必要的医疗干预的情况下进行。然而，无法肯定地预测在分娩过程中不会出现并发症。因此，在许多国家，人们认为最安全的选择是让所有妇女在医院分娩。然而，在一些国家，人们认为只要妇女在怀孕期间得到照顾并在助产士的帮助下分娩，并且可以在家和医院之间进行转移（如果需要），那么在家分娩就是而且可以是产妇护理的一个组成部分。似乎越来越明确的是，由于焦虑和容易获得较多的医疗资源，可能导致更多的干预行为，这反过来有可能进一步诱发新的医疗干预，最终引起本不应该发生的并发症。在计划的家庭分娩中，由经验丰富的助产士协助，并在需要转移时提供医疗协作支持，避免了这些缺点，同时保持了在需要时获得医疗干预的好处。 为什么这很重要？ 越来越多的观察性研究发现，对并发症风险较低的妇女来说，与计划医院分娩相比，由经验丰富的助产士支持并协同医疗支援协助的计划家庭分娩并不比前者更危险，计划医院分娩反而可能导致更多的干预和并发症。与计划在家分娩相比，计划住院分娩的潜在利弊可能与孕妇高度相关。 我们找到了什么证据？ 我们在2021年7月检索了随机对照试验（randomised controlled trials, RCTs）（受试者被随机分配到两个或多个治疗组之一的研究）的证据。除了之前确定的两个非常小的随机对照试验外，没有发...

A number of stipends and bursaries are available to help consumers and other attendees based in developing countries to attend Cochrane Colloquium London 2023. This is our 30th annual flagship event and this year it will take place at Queen Elizabeth II (QEII) Centre in London from 4th to 6th September 2023, and Satellite events on 3rd September.

Stipends and bursaries represent funding you can apply for, if you are eligible, that are intended to help cover registration and other expenses associated with attending the 2023 Colloquium.

Cochrane is providing stipends for:

1. Cochrane Consumers
2. individuals living in low-lower-middle, (LMIC) and upper-middle-income countries (UMIC)

The deadline for applying is 24 April 2023 and winners will be notified 22 May 2023.

Find out whether you are eligible and how to apply

Tuesday, March 7, 2023

脊髓刺激治疗腰背痛 背景 腰背痛是全世界范围内残疾的一个主要成因。脊髓刺激术是一种应用了将电极插入到脊髓中的设备的外科治疗，被推荐用来缓解长期下腰背痛患者的疼痛。本研究目的在于评价将该种手术应用于腰背痛患者的利弊证据。 研究特征 我们在2022年6月10日检索了在线数据库和注册库进行相关研究。我们找到了13项试验，涉及699名受试者。研究中55%的受试者是女性，受试者平均年龄介于47到59岁。受试者腰背痛平均持续时间从5年到12年不等。13项研究中有10项与脊髓刺激术相关产业存在经济利益关联。 主要发现 没有随访超过6个月的研究在受试者中验证脊髓刺激术是否优于安慰剂（假治疗或虚拟治疗）。这表明脊髓刺激术的长期收益尚不明确。已有研究大多数只测量了术后一个月内的结局指标，仅有一项研究测量了术后6个月时的结局指标。 疼痛强度（0~100分，分数越低代表疼痛越轻） 在6个月时，唯一可用的研究发现脊髓刺激术相较于安慰剂没有收益（1项试验，50名受试者；中等质量证据）。6个月时安慰剂组受试者报告其平均疼痛得分为61分，而脊髓刺激术组的报告得分要高4分[+8.2分, -0.2分]。 功能得分（0~100分；分数越低代表功能越好） 在6个月时，一项研究发现与安慰剂相比脊髓刺激组在功能方面（即人体一般身体功能）没有益处（1项试验，50名受试者；中等质量证据）。6个月时安慰剂组受试者报告其功能得分为...

Monday, March 6, 2023

超声用于儿童动脉导管插入 研究背景 动脉导管是一根细管，可插入动脉以监测复杂手术期间和重症监护期间的血压。超声波（一种使用声波捕捉软组织实时图像的成像方法）可以帮助医生定位动脉并插入导管。特别是在儿童中，与其他技术（如触诊动脉（通过皮肤感受脉搏）或多普勒听觉辅助（倾听动脉确切位置处高音的变化）相比，超声可以减少多次针刺的需要、血肿（血管外聚集的血液）和动脉损伤的发生。 我们想要发现什么？ 我们的目的是找出超声是否比动脉触诊或多普勒听觉辅助有任何优势。具体来说，我们想了解超声波是否改善了以下结局。 1.医生初次尝试成功插入导管的频率 2.血流量减少引起的血肿、损伤等并发症的发生 3.医生在前两次尝试中成功插入导管的频率 4.医生在多次尝试插入导管后成功的频率 5.插入导管所需的平均尝试次数 6.插入导管需要多长时间 我们做了什么？ 我们检索了对照临床研究的文献，比较了在18岁以下儿童中使用超声波与传统方法将导管插入动脉。我们比较和总结研究结果，并根据研究方法和规模等因素，评估证据可信度。 我们发现了什么? 我们发现九项符合纳入标准的研究：八项将超声与触诊进行比较，一项将超声与多普勒听觉辅助进行比较。七项研究是桡动脉插管，两项研究是股动脉插管。四项研究未提及任何资金来源，五项研究有部门资金。这些研究纳入年龄从一个月以下到18岁的儿童。 主要研究结果 我们发现，与传统方法相比，超声引导...

通过躯干训练改善脑卒中患者的活动能力 研究背景 脑卒中是一种常见的疾病，可导致成人严重残疾，甚至死亡。脑卒中对人体功能的各个方面都有重要影响，包括运动上的限制。患病后一种常见的缺陷是躯干功能下降，表现为活动能力下降、坐姿平衡能力下降、对内部和外部干扰的反应延迟或减少、躯干的肌肉力量和肌肉激活模式降低。躯干的运动和坐姿平衡对功能独立性都很重要，也就是说，在没有帮助的情况下能够完成日常生活任务，如穿衣、吃饭和梳洗。因此，躯干功能在很大程度上能够预测脑卒中后患者的恢复情况和独立程度。 躯干训练旨在恢复躯干功能，可由不同的元素组成，例如：腹部和背部肌肉的力量训练、专注于提高躯干灵活性的运动；或改善横向或纵向坐位平衡能力的运动。 躯干是身体的核心；它为头部和四肢的控制和运动提供了稳定的基础。躯干训练不仅对躯干功能有积极的影响，对改善日常生活活动、站立平衡、行走和幸福感等其他结局也有效果。 系统综述研究问题 探究躯干训练能否改善脑卒中后人群的日常生活活动、躯干功能、站立平衡、幸福感和其他结局。 文献检索日期 我们检索了九个数据库，并追溯了相关研究的参考文献列表。检索时间截至2021年10月25日。 研究特征 我们纳入了68项研究，共涉及2585名受试者。这些研究随机将受试者分为两组或多组，目的是对比脑卒后的躯干训练与其他疗法或无治疗。 主要研究结果 我们发现躯干训练有可能改善日常生活活动、躯...

新生儿黄疸的间歇光疗与连续光疗 系统综述问题 在患有黄疸的新生儿中，间歇性光疗与连续光疗相比是否能有效降低胆红素水平? 背景 新生儿黄疸是由于胆红素（血液中自然存在的一种黄色化合物）水平高而引起的新生儿皮肤变黄。光疗是目前公认的治疗新生儿黄疸的有效方法。光疗通常持续使用，但间歇性光疗有一些潜在的优势，如改善母亲的喂养和与婴儿的关系。我们不知道间歇性光疗是否与持续光疗一样有效。 研究特征 通过检索截至2022年1月的医学数据库，我们发现有33项研究评估了间歇性光疗对婴儿的效果。其中12项研究（共1600例婴儿）符合纳入标准。一项研究目前正在进行，四项研究正在等待分类。我们关注的主要结局是血清胆红素水平的下降率和胆红素诱导的脑功能障碍（bilirubin-induced brain dysfunction, BIND）。检索截止日期为2022年1月31日。 主要研究结果 我们发现间歇性光疗和连续光疗在降低胆红素水平方面几乎没有差异。连续光疗对早产儿更有效，但我们不知道这是否是一个有意义的差异。间歇性光疗与光疗暴露总小时数的减少有关。间歇性治疗方案在理论上有益处，但有一些重要的安全性结局未得到充分阐明。 证据质量 总体而言，我们将证据质量评为低或极低。我们需要对早产儿和足月儿进行大规模、高质量的试验，才能得出间歇性光疗和连续光疗同样有效的结论。 如果您发现此证据有帮助，请考虑向 Coc...

预防和治疗血管炎型（过敏性紫癜）IgA肾病 研究问题 IgA血管炎 (IgAV)，以前称为过敏性紫癜，是儿童比较常见的小血管炎性疾病，但在成人中较为少见。其症状和体征包括红色丘疹和大片瘀斑（尤其是臀部和腿部）、腹痛、关节痛和肿胀，偶见肠道出血。约三分之一的患儿出现肾脏受累，尿液检测可出现血尿和蛋白尿。大多数患儿肾脏受累较轻（尿液中仅见少量红细胞和蛋白质），能够完全康复，但少数患有持续性肾脏病的患儿可进展为肾衰竭。 研究内容 我们分析了20项随机对照临床试验（randomised controlled trial, RCT），包括1963名受试者。十一项研究纳入了轻度或无肾脏受累的IgAV患儿。五项研究对比了泼尼松（14至28天）与安慰剂或无治疗，五项研究对比了抗凝血药物，一项研究对比了孟鲁司特（通常用于治疗儿童哮喘）与安慰剂。九项研究纳入了中度或重度肾脏受累的儿童。五项研究对比了不同的免疫抑制剂（包括环磷酰胺、麦考酚酸酯、他克莫司、环孢素、来氟米特、硫唑嘌呤）。一项研究对比了血浆置换（去除患者的血浆并用正常血浆代替）、单用环磷酰胺、单用甲泼尼龙，以及两者联用。最后一项研究对比了福辛普利（可减少尿蛋白水平）和无治疗。 研究结果 我们想知道在IgAV发作后6至12个月，这些方式能否预防或治疗持续性肾脏病。研究初期，对于肾脏没有或轻度受累的儿童，我们没有发现泼尼松或其他治疗在防止肾脏进...

Specifications: Fixed Term – 1 Year
Salary: £35,000 per annum  
Location: Ideally based in the UK, Germany or Denmark. Candidates from the rest of the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries (1-year fixed-term contracts)
Directorate: Evidence Production & Methods
Closing date: 13 March, 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters from more than 220 countries. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into five directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Future of Evidence Synthesis (FES) is a critical programme of work for Cochrane over the next 3-5 years. Successful delivery is essential for Cochrane's future and sustainability. A core component of the new production model is the creation of Cochrane Evidence Synthesis Units and Thematic Groups. This role will work closely with the Head of Change Management, to create, launch and manage the initial application process for Evidence Synthesis Units and a second application round for Thematic Groups and help to manage the initial stages of the pilots.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here.
• The deadline to receive your application is 13th March, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, February 27, 2023

不同的生活方式和饮食变化对梅尼埃病有哪些获益和风险？ 关键信息 由于缺乏有力的证据，目前尚不清楚用于治疗梅尼埃病的任何生活方式或饮食变化是否能改善患者的症状，尽管其在临床实践中常规使用。我们也不知道这些干预措施是否存在任何风险。 需要进行更大规模、执行良好的研究，以确定任何生活方式或饮食变化是否有效，并评价其是否有任何有害影响。 还需要做进一步的工作，找出测量梅尼埃病患者症状的最佳方法，以评价治疗是否有获益。这应该包括制定“核心结局集”——一份在所有关于梅尼埃病的研究中都应该测量的结局清单。 什么是梅尼埃病? 梅尼埃病是一种影响内耳的疾病。其会引起反复发作的头晕或眩晕（旋转感），同时伴有听力问题、耳鸣（耳中有鸣响、嗡嗡声）以及耳中的鼓胀感或压迫感。通常影响成年人，并从中年开始发作。 如何治疗梅尼埃病? 口服药物（片剂）通常被用作治疗梅尼埃病的首选药物。其他治疗方案也可供选择（例如耳内注射或手术）。梅尼埃病患者通常被建议改变饮食，例如减少盐或咖啡因的摄入，因为这些被认为会加重疾病症状。 我们想知道什么？ 我们想知道： ——是否有证据表明，任何生活方式或饮食调整都能减轻梅尼埃病的症状； ——这些治疗方案是否会造成任何伤害。 我们做了什么？ 我们检索了将不同类型的生活方式或饮食调整与不调整或假（安慰剂）治疗进行比较的研究。 我们发现了什么？ 我们找到了2项研究，共涉及274名受试者。一...

在梅尼埃病治疗中，直接从耳朵给予庆大霉素有哪些益处和风险？ 关键信息 由于缺乏稳健的证据，尚不清楚直接经耳朵（鼓室内）给予庆大霉素是否能改善梅尼埃病患者的症状。也不清楚治疗是否存在任何风险。 需要进行更大规模、进行得当的研究来确定这种治疗是否有效，并评估是否有任何有害影响。 还需要做进一步的工作来找出如何最好地测量梅尼埃病患者的症状，以评估治疗是否有益。这应该包括制定“核心结局集”——一份在所有关于梅尼埃病的研究中都应该测量的结局清单。 什么是梅尼埃病？ 梅尼埃病是一种影响内耳的疾病。它会导致头晕或眩晕（旋转的感觉）反复发作，并伴有听力问题、耳鸣（耳朵里嗡嗡作响）以及受影响耳朵的饱胀感或压迫感。它好发于成年人，且通常始于中年期。 梅尼埃病如何治疗？ 口服药物（片剂）通常用作梅尼埃病的首选治疗方法。如果这些治疗不能控制症状，则可以将一种称为氨基糖苷类的抗生素直接注入耳内。通常这涉及一种称为庆大霉素的抗生素。最常见的是通过耳膜注射。 我们想知道什么？ 我们想探讨： - 是否有证据表明鼓室内注射氨基糖苷类药物（包括庆大霉素）可以减轻梅尼埃病的症状； - 这种治疗是否可能造成任何伤害。 我们做了什么？ 我们检索了将任何鼓室内氨基糖苷类药物与不治疗或假治疗（安慰剂）进行比较的研究。 我们发现了什么？ 我们找到了五项研究，总共涉及 137 人。它们持续了六个月到两年。所有的研究都着眼于抗生素...

治疗成人中枢性睡眠呼吸暂停的药物 关键信息 这一领域的研究规模较小，我们无法得出与虚拟治疗相比，所研究的任何药物是否对中枢性睡眠呼吸暂停（central sleep apnoea, CSA）患者有效。 什么是中枢性睡眠呼吸暂停？如何治疗？ CSA是一种在睡眠中呼吸反复停止和开始的疾病，是大脑没有向控制呼吸的肌肉发送适当的信号造成的。CSA主要影响男性和心脏病患者。这种情况不同于阻塞性睡眠呼吸暂停，也更不常见，后者是由于气道阻塞或狭窄而导致呼吸中断。CSA的治疗包括使用帮助呼吸的设备，但CSA患者并不总是喜欢使用它们。药物治疗，如催眠药（用于减轻紧张和诱导平静）和呼吸调节剂（用于刺激呼吸），可能是CSA成人患者的一种选择。 本综述想探究什么？ 本综述的目的是发现药物是否可以改善CSA患者的以下结局。 • 中枢性呼吸暂停低通气指数（CSA的一个关键指标，衡量一个人每小时睡眠中呼吸暂停的次数） • 与心脏病有关的死亡 • 睡眠质量 • 生活质量 • 日间嗜睡度 • 呼吸暂停-低通气指数（呼吸暂停的另一个指标） • 任何原因导致的死亡 • 挽救生命的心脏相关干预（例如移植）的时机 此外，我们也想知道这些药物是否会产生不良反应。 我们做了什么？ 我们检索了药物治疗CSA的研究，与不同的治疗方法（如常用于治疗CSA的呼吸装置）、虚拟治疗（安慰剂）、无治疗或常规护理进行比较。受试者必须至少18...

夹板治疗腕管综合征 系统综述问题 本Cochrane综述旨在对比腕部夹板固定与不治疗或其他治疗方式对腕管综合征（carpal tunnel syndrome, CTS）患者的利弊。 研究背景 CTS是指手腕上两条主要神经中的一条受到压迫。这会导致手和手腕疼痛，以及拇指、食指和中指的麻木和刺痛。严重的压迫可能导致手部肌肉萎缩和灵活性丧失。CTS在女性和50岁以上人群中更为常见。 多数CTS患者选择手术治疗，尽管通常情况下先使用非手术疗法，例如夹板、皮质类固醇注射（一种用以减轻炎症的药物）或运动。其中夹板将手腕固定在中立（垂直）位置，而四指和拇指可以自由活动。 研究特征 我们收集并分析了与本综述问题相关的所有研究，共有29项研究评估了夹板治疗CTS的利弊。受试者的平均年龄在42至60岁之间，总数为1937人，其中81%为女性。大多数患者的症状为轻至中度。 主要研究结果 当固定时间少于3个月时，与不治疗相比，夹板可能并不会改善CTS患者的症状和手部功能。然而，与不使用夹板相比，夜间佩戴夹板的多数患者表示，他们感觉整体上有所改善。 从长远来看（超过3个月），由于研究数量较少且研究间结果不一致，我们仍不能确定夹板的益处。我们不能确定夹板治疗是否显著改善了患者的症状或功能。 同时也不确定夹板能否降低再手术率，因为仅三项研究报告了这一结局指标。夹板可能会引起暂时的副作用，如入睡困难或取下夹板后...

正压疗法治疗梅尼埃病的益处和风险是什么？ 关键信息 目前，由于缺乏稳健证据，正压疗法是否能改善梅尼埃病人的症状仍然存疑。我们没有发现任何关于这种治疗方法是否会造成伤害的信息。 为了确证正压疗法是否有效，并确保治疗不会产生不良反应，需要进行更大规模、更完善的研究。 还需要做进一步的研究，来找出衡量梅尼埃病患者症状的最佳方法，以评估治疗是否有效。这应该包括制定"核心结局指标集"— 一份在所有关于梅尼埃病的研究中都应该测量的结局清单。 什么是梅尼埃病 梅尼埃病是一种内耳疾病。它会引起反复发作的头晕或眩晕（旋转感），同时伴有听力问题、耳鸣（耳中有鸣响、嗡嗡声）以及耳朵的充盈感或压迫感。它通常影响成年人，并从中年开始发作。 如何治疗梅尼埃病？ 口服药物（片剂）和生活干预常常被用作梅尼埃病的首选治疗方法。如果这些方法对控制症状不起作用，那么可以尝试其他治疗。这包括正压疗法，即在耳朵里插入一根与泵相连的管子。该泵产生压力波，这可能有助于缓解梅尼埃病的某些症状。通常情况下，人们每次使用泵约5分钟，每天最多3次。 我们想发现什么 我们想探讨： -是否有证据表明正压疗法对减轻梅尼埃病的症状有效； -正压疗法是否会导致任何伤害。 我们做了什么 我们检索了比较正压治疗与不施加干预措施或假性（安慰剂）治疗的研究。 研究结果 总共纳入3项研究，涵盖238位受试者。这些研究最多持续四个月，所以我们没有任何关于...

Watch videos from the recent event held by Cochrane PaPaS

For 23 years the Cochrane Pain, Palliative and Supportive Care (PaPaS) group has been delivering the gold standard in evidence synthesis in the field of pain management, palliative and supportive care and supporting the community towards better methods and standards in pain clinical trials and systematic reviews. As their funding comes to an end, they highlighted and celebrated their contribution with an event, called ‘Truth, Integrity and the Future of Pain Evidence’ at the Wellcome Collection in London, UK.  It was a chance to reflect on what has been discovered, where we continue to face important challenges, and how we might move toward a future of trusted evidence to guide better pain care globally.

Dr. Neil O’Connell, Cochrane PaPaS Editor explains the importance of the event; “Working in evidence synthesis we can achieve a “birds-eye” view of the evidence ecosystem in our field, including its problems. Pain in clinical practice and patient care is often poorly served by an evidence architecture containing multiple structural weaknesses. These issues span pre-clinical research, clinical trials, and systematic reviews, and impact upon developing clinical guidelines. Clinical practice in pain management frequently diverges from the evidence, or evolves in the absence of evidence, driven by individual and organisational vested interests, market forces, fashion, and demand from people with pain. In our event, we heard from a range of established and emerging leaders in the field to better understand the challenges and to consider how we create better solutions.”

Talks at the meeting highlighted a range of challenges to the quality and trustworthiness of pain evidence across the pipeline, from pre-clinical through to evidence synthesis, and focused on approaches to improving that picture through better methods, open science practices, interdisciplinary working and partnership with people with lived experience of pain. There was an exceptional range of speakers and leaders in terms of discipline, perspective, and career stage. The audience was also diverse, representing clinicians across many disciplines, researchers, people with pain, editors, and publishers. It was a great day, with comments from one attendee saying it was their most thought-provoking event of the year.

• Read about the events of the day on Twitter under #PaPaSPain2022
• Watch videos from the event

Wednesday, February 22, 2023

Cochrane is made up of 11,000 members and over 67,000 supporters come from more than 130 countries, worldwide. Our volunteers and contributors are researchers, health professionals, patients, carers, people passionate about improving health outcomes for everyone, everywhere.

Getting involved in Cochrane’s work means becoming part of a global community. The Cochrane International Mobility programme connects successful applicants with a placement in a host Cochrane Group, learning more about the production, use, and knowledge translation of Cochrane reviews. The prgramme offers opportunities for learning and training not only for participants but also for host staff.

In this series, we profile those that have participated in the Cochrane International Mobility Program and learn more about their experiences.

Name: Chiara Russo
Location: Italy
Cochrane International Mobility location: Cochrane Sweden

How did you first learn about Cochrane?
When I first heard about Cochrane it was a coincidence. I was studying at my University in Genoa (Italy) and I was looking for a place to go for my Erasmus Traineeship Program. As I was interested in pediatrics field, a medical doctor suggested me to contact Matteo Bruschettini and he offered me the opportunity to go to Sweden, where I worked with him at Cochrane Sweden.

What was your experience with your Cochrane International Mobility?
Actually, before going to Sweden, I’d never had any research experience. Matteo offered me the opportunity to approach systematic reviews, at first with Cochrane Interactive Learning modules, then I had the pleasure to actively work on systematic reviews.

What are you doing now in relation to your Cochrane International Mobility experience?
Once I completed my four-month placement at Cochrane Sweden, I continued to work with Matteo. Thanks to him, I’m co-author of a published Cochrane review, which has already been updated. Moreover, I completed, with Cochrane Sweden and other co-authors, another Cochrane review, which is in press, commissioned by the WHO (World Health Organization).  Even when I came back to Italy, Matteo is still supportive and available for any of my concerns.

Do you have any words of advice to anyone considering a Cochrane International Mobility experience?
I really suggest to anyone interested in research to connect to Cochrane. It will be a great experience both for a first approach to research and for the more experienced medical doctor. Not only will you probably have the opportunity to actively collaborate to a systematic review, but you will certainly learn how to read scientific text. It will also be an opportunity to meet people and other cultures from all over the world.

 

 

 

Wednesday, February 22, 2023

告知肌萎缩性侧索硬化症/运动神经元疾病患者其诊断结果的方法 系统综述问题 本综述旨在评价关于沟通肌萎缩性侧索硬化症（amyotrophic lateral sclerosis, ALS）或运动神经元疾病（motor neuron disease, MND）诊断结果的证据。 研究背景 ALS，也被称为MND，是一种影响运动神经的疾病。该疾病会导致渐进性失能，包括肢体无力、呼吸困难以及发音和吞咽问题。最重要的是，ALS/MND患者须接受此疾病通常在发病三到五年内死亡的事实。初次诊断时，ALS/MND患者、亲属和照护者可能会经历巨大的痛苦，因此，懂得如何告诉他们诊断的结果非常重要。本系统评价广泛检索了关于ALS/MND病情告知沟通方法的随机对照试验（randomised controlled trials, RCT）。 研究结果 没有发现任何关于ALS/MND病情告知沟通方法的RCT。 研究检索截至2022年2月。 如果您发现此证据有帮助，请考虑向 Cochrane 捐款。我们是一家慈善机构，提供可获取的证据来帮助人们做出健康和护理决定。捐赠 作者结论:  目前没有RCT评价不同的沟通策略，以向被诊断为ALS/MND的人传达坏消息。 需要有针对性的研究来评价不同沟通方法的有效性和效果。 阅读摘要全文…… 研究背景:  肌萎缩性侧索硬化症（Amyotrophic la...

Meet our #CochraneLondon Social Media Ambassador volunteers who will be helping to share the content of the London Colloquium and their experience at the colloquium on social media. They will be sharing content across all your favourite social media platforms.

Cochrane UK is hosting Cochrane’s Colloquium taking place in London, UK from 4-6 September 2023. With the theme “Forward together for trusted evidence”, the 2023 Cochrane Colloquium is set to be a groundbreaking event with a mix of learning, networking, plenary speakers, events, and more! 

The #CochraneLondon Ambassadors are attending the colloquium and will be sharing the exciting experience before, during, and after the event. They will not act as spokespersons for Cochrane but will share their own take on the experience. The Ambassadors will use their social media platforms to provide insights into the Colloquium's discussions, key takeaways, their favourite keynotes, and provide some behind-the-scenes posts about what it's like to attend and who from the Community they meet. 

You can find Cochrane on X, Facebook, YouTube, and Instagram. Follow the #CochraneLondon platform on all your favourite platforms or give your favourite ambassadors a follow.

Claire Alllen
Social Media: X

Claire Allen worked with Cochrane from 1997-2014, during which time Evidence Aid was created (in 2004) with Cochrane colleagues. Evidence Aid aims to save lives and livelihoods in disasters by providing decision-makers with the best available evidence and by championing its use. In 2014 she moved over to being staff at Evidence Aid and has since managed the day-to-day operations of the independent charity.

Claire Allen has attended 18 Colloquiums in the past! She will be joining the Library of People on Wednesday’s lunch break where she will be an “open book”. She is looking forward to chatting with attendees about translating evidence to support disaster settings as well as catching up with Cochrane colleagues, attending plenaries, and workshops – and sharing insights along the way on social media.

Claire will be sharing takeaways from her Cochrane London experience on the main Evidence Aid X account. Follow Evidence Aid and experience the Colloquium alongside Claire and learn more about how evidence can support decision-makers! 

Dr. Nikita Burke
Social Media: X accounts for Evidence Synthesis Ireland, Cochrane Ireland, and Nikita's personal X account

Dr. Nikita Burke is the Programme Manager for Evidence Synthesis Ireland, which aims to build knowledge, awareness and capacity in evidence synthesis on the island of Ireland and beyond. She is also the Associate Director for Cochrane Ireland. 

Nikita has a curiosity and commitment to public involvement and engagement in health research, and knowledge translation and communication of evidence. She has worked with Cochrane Crowd to develop educational modules for the public on key steps in a systematic review and study designs.

This is Nikita’s first Cochrane Colloquium! She is looking forward to meeting colleagues and public partners, many in person for the first time! Follow her on  @EvidSynIrl, @CochraneIreland, or @nikitanburke for public involvement, co-production, capacity building and communication of evidence content.

Sarah Chapman
Social Media: X

Sarah Chapman is a Knowledge Broker at Cochrane UK and she is an editor a writer for the Evidently Cochrane Blog. She also has a personal blog, From Ear To Eternity, where she writes about her cochlear implant journey and about life with hearing loss. Her interests include best practices for sharing health evidence on social media and patient involvement in health research. 

This is Sarah's seventh Colloquium and the second time being part of the Local Organizing Committee. She is looking forward to welcoming everyone to London and dancing under the dinosaurs at the social night. 

Sarah will be sharing behind-the-scenes images of the Colloquium and all the extra bits beyond the main content events. Follow Sarah to also learn more about how Cochrane involves patients and advocates in their work. 

Claudio Cordani
Social Media: Instagram, X

Claudio Cordani is a Physiotherapist from Italy. He completed a Master of Science in 2019 and is now attending a Ph.D. in Clinical Research. Since 2021, he has been a member of Cochrane Rehabilitation, following special projects on evidence synthesis in the rehabilitation field. Claudio is passionate about neurological and musculoskeletal rehabilitation as well as clinical research.

This is Claudio's first Cochrane Colloquium and he is looking forward to meeting some research peers in the unique and historical background of London. He is excited about the opportunity to learn more about methodology, healthcare decision-making, stakeholder engagement, and evidence implementation. Claudio has contributed to the oral communication entitled “The concept of “evidence relevant to” in the rehabilitation field: post COVID-19 condition mapping for the World Health Organization Guidance”, which will be presented by Prof. Stefano Negrini on September 4th at “Mapping evidence” session. 

Claudio will be posting about his experience on his personal Instagram and his personal X account and will be tagging Cochrane Rehabilitation on Instagram and Cochrane Rehabilitation on X, so you can also follow the official account for his reposts. 

 

Megha Garg
Social Media: LinkedIn

Megha works as Systematic Review Scientist and is the editor-in-chief of a renowned journal along with being the editorial team member for many others. Her interests include best practices and methods behind evidence synthesis, with a focus on quality and bias assessment in published literature.

This is Megha's first Cochrane Colloquium! She is looking forward to engaging with healthcare decision-making experts to explore the challenges in healthcare data and working 'forward together for trusted evidence' while enjoying the stunning views across the London skyline to prominent historic landmarks.

Follow Megha on LinkedIn and go behind the scenes! She will be reporting live from the Colloquium to share some of the insights from each day and take you through the talks, workshops, and other activities and presentations.

 

Ella Flemyng
Social Media: X, LinkedIn

Ella is Cochrane's Interim Head of Editorial Policy and Research Integrity and is on the Editorial Board of Cochrane's new, open access journal, Cochrane Evidence Synthesis and Methods. She is interested in research integrity, reliability, and the methods behind evidence synthesis.

She is looking forward to immersing herself in research integrity and methodology topics and networking with experts at the Colloquium. She is particularly excited about the 2023 Cochrane Methods Symposium.

Ella shares developments in evidence synthesis methodology, research integrity and publication ethics on social media. Follow Ella and learn from all the posters and presentations she will be attending and sharing.

Margarida Freitas
Social Media: personal Instagram and Cochrane Rehabilitation Instagram

Margarida Freitas is a Medical Doctor and Physical and Rehabilitation Medicine specialist from Portugal. She has been involved with clinical research and team managing and development since Medical School. Since 2020, she has been Cochrane Rehabilitation's Translation Manager, managing a team of translation partners who speak a total of 13 languages. Margarida is passionate about Rehabilitation, Dance Medicine, and clinical research and she is about to start her PhD journey. 

This is Margarida's first Cochrane Colloquium! She is looking forward to meeting some research peers in the vibrant, yet historical London city. She is thrilled to return to the UK, where she has spent some months in observational clinical rotations. She won't miss the opportunity of learning more about healthcare decision-making, statistics and methodology. Margarida will present an oral communication about the cooperative framework of Cochrane Rehabilitation's blogshot translation, so make sure you don't miss the "Building partnerships and implementing evidence" session.

She will be posting as much as she can on her personal Instagram account – @margarida_mota_freitas - and she will be tagging @cochrane.rehabilitation, so you can also follow the official account.

Dr Pradnya Kakodkar
Social Media: LinkedIn, YouTube 

Meet Dr Pradnya Kakodkar; an independent Education and Research Consultant from India. She is a dedicated Cochrane member and passionately conducts webinars to promote the findings of Cochrane systematic review in dental practice. These webinars aim to bridge the gap between research and clinicians, facilitating effective knowledge translation and benefiting the general public in dental practice.  

This is Pradnya’s first Colloquium! She is extremely excited to present her work in poster form and share her Colloquium experiences with you.

Stay connected with Pradnya on LinkedIn and YouTube as she will be sharing personal insights from the experience of presenting at the Colloquium and attending for the first time,  valuable perspectives from experts, and noteworthy takeaways from sessions she will be attending.

Katie Lamb
Social Media: Instagram, X, LinkedIn 

Katie is an artist and advocate for children and young people living with diabetes and has lived with type one diabetes for twenty years. Her interests include ensuring the voices of young people are heard in research, and using arts and creativity to share lived experiences. Katie is an Expert by Experience for the Diabetes UK Research Steering Group for children and young people and a diabetes advocate with the Dedoc Voices programme.

This is Katie’s first Cochrane Colloquium! She is looking forward to meeting researchers and consumer volunteers, and the opportunity to learn from experts. Katie is most excited about sessions focused on co-design and communicating evidence.

Follow Katie to see how healthcare consumers are involved in the event and the main takeaways from the sessions she attends. Katie uses Instagram to share event highlights through art and creative summaries. 

Toby Lasserson
Social Media: Twitter

Toby is the Deputy Editor in Chief of the Cochrane Library and Cochrane's Head of Methods & Evidence Synthesis. 

This is Toby's 18th Colloquium! He is especially excited to attend the Methods Symposium happening the day before and the Annual General Meeting.

Follow Toby as he shares witty and pun-filled tweets about Cochrane evidence, the methodology behind meta-analysis and systematic reviews, and live tweets with takeaways from plenary speakers at the Colloquium. 

Richard Morley
Social Media: X, LinkedIn 

Richard works for Cochrane as the Consumer Engagement Officer, supporting the engagement and involvement of healthcare consumers (patients, carers, and the public) in Cochrane's work.  

This is Richard's fourth Colloquium experience. He is part of Cochrane London's  Local Organizing Committee and is chair of the Consumer Stiped Committee. He is especially looking forward to meeting with some of the consumer volunteers in-person and the meetings before the Colloquium begins. 

Follow Richard to learn more about how the Colloquium is a Patients Included event and what things have been done behind the scenes to make the event accessible. 

Roses Parker
Social Media: X

Meet Roses Parker, Cochrane's Commissioning Editor who possesses a wealth of knowledge and experience. With a PhD in Nursing focusing on pain management in children with cancer, Roses has made significant contributions to Cochrane in various capacities. Her involvement spans a wide range of crucial tasks, from coordinating priority-setting work, using data to commission updates, and being an author on the updated 'Cochrane logo review'.

Roses eagerly anticipates attending her second Colloquium! She is particularly excited about the Methods Symposium preceding the main event, as it promises to delve into the latest advancements in equity in evidence synthesis. Roses will also be giving a presentation at the Colloquium about Cochrane's important role in improving health equity and how others can get involved. Roses aims to provide some real-time updates through her X account, capturing the essence of the workshops, plenaries, and other noteworthy events she will be attending.

Join Roses on an inspiring journey through her live tweets, as she takes you along to experience the immersive Colloquium first-hand and unveils invaluable insights from the captivating presentations she attends.

Muriah Umoquit
Social Media: X, Cochrane Instagram Stories

Muriah is Cochrane's Senior Communications Officer and runs the social media for Cochrane and Cochrane Library. 

This is Muriah's fourth Colloquium. She is looking forward to seeing everyone use the wonderful #BetterPoster templates and connecting with the community through Colloquium social events,  such as the book exchange, the Anne Anderson Walk, and the Gala night. 

Follow Muriah for tips and best practices for making the most of attending a conference on social media. She will also be sharing short interviews and behind-the-scenes videos on Cochrane's Instagram stories during the colloquium.  

 Dr. Elpida Vounzoulaki
Social Media: X

Elpida Vounzoulaki is a Postdoctoral Epidemiologist at the Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester and Chair of the Cochrane Early Career Professionals (ECP) Steering Group. She is also the host of Cochrane ECP's first podcast, Conversations with Cochrane.

This is Elpida's first time attending a Cochrane event and she is really excited to meet Cochrane members and volunteers, as well as speakers attending the event!

Follow Elpida on X and learn about what is going on at ''Putting evidence into practice'' on Sunday 3 September and the exciting opportunities to get involved with Cochrane as an Early Career Professional!

Find out more about the Colloquium:

• View and update your schedule
• Visit the Colloquium website
• ‘Take a break activities

 

Thursday, August 24, 2023

Monday, February 20, 2023

Friday, February 17, 2023